Caudal Regression Syndrome with Partial Agenesis of the Corpus callosum and Partial Lobar Holoprosencephaly : Case report

Authors

Hilal Al Hashami, Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman
Maria F. Bataclan, Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman
Mariam Mathew, Departments of Obstetrics and Gynecology, Sultan Qaboos University Hospital, Muscat, Oman
Lalitha Krishnan, Departments of Child Health, Sultan Qaboos University Hospital, Muscat, Oman

Abstract

Caudal regression syndrome is a rare fetal condition of diabetic pregnancy. Although the exact mechanism is not known, hyperglycaemia during embryogenesis seems to act as a teratogen. Independently, caudal regression syndrome (CRS), agenesis of the corpus callosum (ACC) and partial lobar holoprosencephaly (HPE) have been reported in infants of diabetic mothers. To our knowledge, a combination of all these three conditions has not been reported so far.

Publication Date

4-17-2010

First Page

89

Last Page

93

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Hashami, Hilal Al; Bataclan, Maria F.; Mathew, Mariam; and Krishnan, Lalitha (2010) "Caudal Regression Syndrome with Partial Agenesis of the Corpus callosum and Partial Lobar Holoprosencephaly : Case report," Sultan Qaboos University Medical Journal: Vol. 10: 89-93.
DOI: https://doi.org/10.18295/2075-0528.1164