Severe Hyperparathyroidism Versus Parathyroid Carcinoma : A clinical dilemma

Authors

Mariam Al-Fadhli, Departments of Medicine, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait
Suhail A R. Doi, Departments of Medicine, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait and School of Population Health, University of Queensland, Brisbane, Australia
Thomas Muttikkal, Departments of Radiology, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait
Basel Al-Sumait, Departments of Surgery, Mubarak Al-Kabeer Teaching Hospital, Jabriya, Kuwait

Abstract

No clinical or laboratory data allow a preoperative diagnosis of parathyroid carcinoma and only occasionally does a definitive finding differentiate an adenoma from a carcinoma. We present a case of primary hyperparathyroidism presenting with severe elevation of parathyroid hormone and serum calcium as well as complications. We go on to discuss the case in the light of a literature review. The severity of the elevation of the parathyroid hormone, other biochemical alterations, the presence of skeletal and renal complications and of a neck mass should alert the clinician to a possible parathyroid carcinoma. Radical surgery is the only effective therapy for parathyroid carcinoma, and should always be performed if a preoperative suspicion is entertained.

Publication Date

4-17-2010

First Page

94

Last Page

100

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Al-Fadhli, Mariam; Doi, Suhail A R.; Muttikkal, Thomas; and Al-Sumait, Basel (2010) "Severe Hyperparathyroidism Versus Parathyroid Carcinoma : A clinical dilemma," Sultan Qaboos University Medical Journal: Vol. 10: 94-100.
DOI: https://doi.org/10.18295/2075-0528.1165