Nodular Melanoma Mimicking Keratoacanthoma : Lessons to learn

Authors

Leelavathi Muthupalaniappen, Departments of Family Medicine, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Srijit Das, Departments of Anatomy, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Norazirah Md No, Departments of Dermatology Unit, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Siti A. M. Ali, Departments of Pathology, Medical Faculty, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Abstract

A 67-year-old man of Chinese descent presented with a painless nodular lesion that had been present on his right forearm for the previous 3 months. A single, well-defined, dome-shaped, firm nodule with a central keratin plug surrounded by erythema was noted. Keratoacanthoma with secondary bacterial infection was suspected and the patient underwent an excision biopsy. Biopsy of the nodule and immunohistochemical staining supported a diagnosis of nodular malignant melanoma. It should be noted both that nodular malignant melanoma may present with a wide variety of clinical appearances, and that the lack of melanin pigment in nodular malignant melanoma may hinder the diagnosis of this aggressive tumour.

Publication Date

7-15-2012

First Page

360

Last Page

363

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Muthupalaniappen, Leelavathi; Das, Srijit; No, Norazirah Md; and Ali, Siti A. M. (2012) "Nodular Melanoma Mimicking Keratoacanthoma : Lessons to learn," Sultan Qaboos University Medical Journal: Vol. 12: 360-363.
DOI: https://doi.org/10.18295/2075-0528.1389