Abstract
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Involvement of the nervous system, either primary or secondary, is common in SLE, and 19 different neuropsychiatric clinical syndromes have been recognised in association with the disease. Several pathophysiological mechanisms have been implicated in the pathogenesis of neuropsychiatric SLE (NPSLE), including vasculopathy, autoantibodies, and cytokine-mediated tissue injury. Careful evaluation of the patient is required to rule out secondary causes before attributing the neurological symptoms to SLE. Treatment depends on the nature and severity of NPSLE syndrome.
Publication Date
2-27-2013
First Page
19
Last Page
25
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Alkhotani, Amal
(2013)
"Neuropsychiatric Lupus,"
Sultan Qaboos University Medical Journal: Vol. 13: 19-25.
DOI: https://doi.org/10.18295/2075-0528.1425
