Abstract
Disseminated herpes simplex virus (HSV) is a known fatal condition in neonates and immunocompromised patients. However, very few cases have been reported in an immunocompetent host. We report a 1-year-old female child who presented to a children's hospital in Riyadh, Saudi Arabia, in 2022. She was previously healthy and presented with febrile illness associated with decrease conscious level. Upon examination, the patient had markedly elevated liver enzymes. A cerebrospinal fluid (CSF) polymerase chain reaction (PCR) finding of HSV as well as positive HSV IgM serology resulted in a diagnosis of disseminated HSV (encephalitis/hepatitis). She received acyclovir course and during follow-up for 1 year showed excellent developmental outcome.
Publication Date
3-20-2025
First Page
137
Last Page
140
Creative Commons License
This work is licensed under a Creative Commons Attribution-No Derivative Works 4.0 International License.
Recommended Citation
Adedeji, Idris A.; Abdullahi, Abdulrahim; Alharbi, Abdulmohsen S.; Abusrair, Fatimah; and Alshehri, Mohamed
(2025)
"Disseminated Herpes Simplex Virus-1 in Previously Healthy Child Without Skin Rash: Case report and literature review,"
Sultan Qaboos University Medical Journal: Vol. 25: 137-140.
DOI: https://doi.org/10.18295/squmj.6.2024.042
